Three Ways to Slow the Spread of BRSV

Bovine respiratory syncytial virus (BRSV) is an aggressive, fast-acting disease that often opens the door to other infectious pathogens that cause bovine respiratory disease (BRD) in calves and their dams. Because the virus itself is not treatable, the question quickly becomes “What can we do to prevent this virus and ultimately prevent the onset of BRD?”

Although we may not be able to treat BRSV, there are steps you can take to safeguard your herd from the virus.

No. 1: Concentrate on colostrum

The first and one of the most important kinds of protection we can provide calves is quality colostrum. Newborn calves are born with a naïve immune system, and rely on high-quality colostrum to provide immunity against BRSV and other infectious agents.

Research has shown that up to 60% of maternal colostrum fed to newborn dairy calves may be inadequate.1 To make certain your calves are getting the quality colostrum they need, focus on three areas:

· Start with your dry cows. Provide a comfortable, stress-free environment with proper nutrition. This puts them in the best possible position to give birth to a healthy calf and produce quality colostrum.

· Vaccinate the dam. Killed vaccines, safely administered at the beginning of the dry cow period, are another way to keep the dam healthy and enhance antibody levels found in colostrum.2 Cows vaccinated during the dry period are also more likely to enter the next lactation with a robust immune system to fight off infectious-disease threats.

· Give colostrum right away. It is recommended calves receive 10% to 12% of their body weight in colostrum within one to two hours of birth.3

No. 2: Keep calves clean and comfortable

We also want to ensure newborn calves are kept in a stress-free, clean environment with good ventilation. An ample supply of dry bedding will promote calf comfort and decrease the risk of disease, while proper ventilation will keep calves from inhaling dust and harmful disease-causing pathogens.

If possible, keep calves from spreading respiratory disease by preventing nose-to-nose contact. For paired- or group-housed calves, reduce the risk by refraining from overcrowding, and by ensuring calves have enough space to eat. If you are housing two or three calves per pen, it’s still important to prevent nose-to-nose contact between pens.

A calf’s immune system can become compromised when exposed to dramatic weather fluctuations. Although the weather is a factor out of our control, your facilities should have the capacity to keep calves protected from the elements and temperature changes.

No. 3: Vaccinate for BRSV

As the passive immunity from colostrum wanes, vaccination is required to jump-start acquired immunity. I encourage all producers to incorporate BRSV protection into their vaccination program.

If deemed beneficial, calves can be vaccinated soon after birth with intranasal vaccines, and again around 30 days of age with injectable modified-live virus (MLV) vaccines. Antibodies absorbed from colostrum can interfere with the development of immunity from MLV vaccines for several months after birth, so it’s also important to administer an MLV vaccine proven to develop immunity in calves even in the presence of maternal antibodies.

Despite all the things we do to keep calves healthy, we are still going to see BRSV develop. You can do your part to limit the incidence and severity of the disease by working with a veterinarian to fine-tune your prevention plan.


1 Morrill KM, Conrad E, Lago A, et al. Nationwide evaluation of quality and composition of colostrum on dairy farms in the United States. J Dairy Sci 2012;95(7):3997–4005.

2 Smith B, Rieger R, Dickens C, et al. Anti-bovine herpesvirus and anti-bovine viral diarrhea virus antibody responses in pregnant Holstein dairy cattle following administration of a multivalent killed virus vaccine. Am J Vet Res 2015;76(10):913–920.

3 Godden SM, Lombard JE, Woolums AR. Colostrum management for dairy calves. Vet Clin North Am: Food Anim Pract 2019;35(3):535–556.

Learn more about Boehringer Ingelheim Animal Health USA at bi-animalhealth.com.


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